Journal of Clinical Medicine Research

Frequency: Monthly
Editor-in-Chief: Richard Liu, MD, Elmer Press, Toronto, Canada
Journal Access: Open Access
ISSN-print: 1918-3003
ISSN-online: 1918-3011
Journal scope: All disciplines of clinical medicine, medical research and clinical practice, preventive medicine, epidemiology, nursing, and healthcare research, clinically focused, evidence-based medicine.
Indexed and covered: PubMed, PubMed Central, Chemical Abstract (CA), EBSCO, Worldcat, JournalTOCs, Google, Google Scholar, Clarivate Analytics Links- Journal Title List.

Journal archiving and digital preservation:


  • Assessment of Serum Vitamin B12 Levels and Other Metabolic Parameters in Subjects With Different Values of Bone Mineral Density

    Controversial experimental and clinical evidences have raised questions regarding the role of B12 and insulin-like growth factor 1 (IGF-1) on osteoblast function and bone health. In this study, we aimed to determine if the serum levels of B12, IGF-1 and procollagen type 1 N-terminal propeptide (P1NP) are associated with different degrees of bone mineral density (BMD).

  • Does Red Cell Distribution Width Predict Outcome in Traumatic Brain Injury: Comparison to Corticosteroid Randomization After Significant Head Injury

    Traumatic brain injury (TBI) is a leading cause of death and disability. The role of red cell distribution width (RDW) as a prognostic biomarker for outcome in TBI patients is unknown. Based on the corticosteroid randomization after significant head injury (CRASH) trial database, a prognosis calculator (CRASH) has been developed for outcome prediction in TBI.

  • A Multiple Treatment Comparison of Eleven Disease-Modifying Drugs Used for Multiple Sclerosis

    Several disease-modifying drug therapies are available for the treatment of multiple sclerosis (MS). To ensure the most appropriate MS management, we assessed the effectiveness and cost-effectiveness of the disease-modifying medicines used for MS.

  • Predictors of Recurrent Hospital Admission for Patients Presenting With Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State

    Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are two serious, preventable complications of diabetes mellitus. Analysis of variables associated with recurrent DKA and HHS admission has the potential to improve patient outcomes by identifying possible areas for intervention.

  • Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation

    The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt.

  • Hypertension Prevalence, Awareness and Blood Pressure Control in Matao, Brazil: A Pilot Study in Partnership With the Brazilian Family Health Strategy Program

    Around 30% of Brazilian population is hypertensive. Brazilian’s Family Health Strategy (FHS) is a community-based approach to provide primary health care and control chronic disease as hypertension. The aims of this pilot study were to study hypertension prevalence and awareness and to analyze the feasibility of FHS program with community healthy agents (CHA)...







An Improvement of Cardiovascular Risk Factors by Omega-3 Polyunsaturated Fatty Acids
An epidemiological survey in the Northwest Greenland reported that the Greenlanders have a lower frequency of acute myocardial infarction and diabetes mellitus. The very low incidence of ischemic heart disease in the Greenlanders was explained by consumption of a diet rich in omega-3 polyunsaturated fatty acids (PUFAs).Full Text

Validation of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA)
It has been suggested to replace the diagnosis-specific graded prognostic assessment (DS-GPA, based on performance status and number of brain metastases) for patients with primary malignant melanoma with the new Melanoma-molGPA. The latter is a more complex assessment, which also includes BRAF mutation status, age and extracranial metastases. Full Text

Image of the Issue

Successful Treatment of Rapidly Progressive Life-Threatening Esophageal Submucosal Hematoma in a Patient With van der Hoeve Syndrome
Osteogenesis imperfecta (OI) is a rare inherited disorder of the connective tissue with many reports on its association with bleeding diatheses. OI patients with blue sclera, hearing loss, and bone vulnerability are classified as having van der Hoeve syndrome. Here, we report the first case of rapidly progressing, massive esophageal submucosal hematoma in this syndrome. Full Text

Video Report

Isolated Right Ventricular Dilated Cardiomyopathy: An Early Diagnosis
Because of an incomplete right bundle branch block, a severe right ventricular dilatation with no left ventricular cardiomyopathy was found in a 44-year-old man. Magnetic resonance and transesophageal echocardiography confirmed the finding and these tests also failed to find any potential cause. A pulmonary hemodynamic study and a coronary angiography were strictly normal. Full Text

Current Issue

Past Issues

Vol. 10, No. 5, May 2018

Table of Contents


Exercise Therapy for Patients With Type 2 Diabetes: A Narrative Review Abstract HTML PDF
Hidekatsu Yanai, Hiroki Adachi, Yoshinori Masui, Hisayuki Katsuyama, Akiko Kawaguchi, Mariko Hakoshima, Yoko Waragai, Tadanao Harigae, Hidetaka Hamasaki, Akahito Sako 365-369
The Main Anatomical Variations of the Pancreatic Duct System: Review of the Literature and Its Importance in Surgical Practice Abstract HTML PDF
Ioannis Dimitriou, Anastasios Katsourakis, Eirini Nikolaidou, George Noussios 370-375

Original Article

The Impact of the Underlying Risk in Control Group and Effect Measures in Non-Inferiority Trials With Time-to-Event Data: A Simulation Study Abstract HTML PDF Suppl1
Xuanqian Xie, Chenglin Ye, Nicholas Mitsakakis 376-383
Impact of Drug Induced Long QT Syndrome: A Systematic Review Abstract HTML PDF
Karuppiah Arunachalam, Seetha Lakshmanan, Abhishek Maan, Narendra Kumar, Paari Dominic 384-390
Sidestream Dark Field Imaging of the Microcirculation to Assess Preeclampsia Microvascular Dysfunction Abstract HTML PDF
Amelie Pelland, Ronald B. George, Christian Lehmann, Jillian Coolen 391-395
Fecal Calprotectin: A Comparison of Two Commercial Enzymoimmunoassays and Study of Fecal Extract Stability at Room Temperature Abstract HTML PDF
Delia Acevedo, Maria Pilar Salvador, Javier Girbes, Nuria Estan 396-404
Effects of a Low Advanced Glycation End Products Diet on Insulin Levels: The Feasibility of a Crossover Comparison Test Abstract HTML PDF
Shin Sukino, Shinsuke Nirengi, Yaeko Kawaguchi, Kazuhiko Kotani, Kokoro Tsuzaki, Hiroshi Okada, Akiko Suganuma, Naoki Sakane 405-410
Anxiety and Depression Among Adult Patients With Diabetic Foot: Prevalence and Associated Factors Abstract HTML PDF
Ali Ahmad, Mousa Abujbara, Hashem Jaddou, Nidal A. Younes, Kamel Ajlouni 411-418
The Role of Urinary Neutrophil Gelatinase-Associated Lipocalin in Predicting Acute Kidney Dysfunction in Patients With Liver Cirrhosis Abstract HTML PDF
Abdulrahman A. Aljumah, Hani Tamim, Mohamed Saeed, Waleed Tamimi, Hanan Alfawaz, Salem Al Qurashi, Abdulaziz Al Dawood, Abdulla Al Sayyari 419-428
Accuracy of Three-Dimensional Planning in Surgery-First Orthognathic Surgery: Planning Versus Outcome Abstract HTML PDF
Ngoc Hieu Tran, Syrina Tantidhnazet, Somchart Raocharernporn, Sirichai Kiattavornchareon, Verasak Pairuchvej, Natthamet Wongsirichat 429-436
The Prevalence and Implication of Zinc Deficiency in Patients With Chronic Liver Disease Abstract HTML PDF
Kazuhiro Katayama, Takumi Kawaguchi, Koichi Shiraishi, Toshifumi Ito, Kazutomo Suzuki, Chizu Koreeda, Takaaki Ohtake, Motoh Iwasa, Yoshio Tokumoto, Ryujin Endo, Naohiro Kawamura, Makoto Shiraki, Tatsunori Hanai, Daiki Habu, Satoru Tsuruta, Hironori Sakai, Yoshiyuki Miwa, Norifumi Kawada, Akinobu Kato, Yoshiyuki Takei, Tetsuya Mine, Yutaka Kohgo, Toshihito Seki, Michio Sata, Yuri Ito, Keisuke Fukui, Shuhei Nishiguchi, Hisataka Moriwaki, Kazuyuki Suzuki 437-444
Standardized Reporting System Use During Handoffs Reduces Patient Length of Stay in the Emergency Department Abstract HTML PDF Suppl1
Robert T. Dahlquist, Karina Reyner, Richard D. Robinson, Ali Farzad, Jessica Laureano-Phillips, John S. Garrett, Joseph M. Young, Nestor R. Zenarosa, Hao Wang 445-451




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Journal of Clinical Medicine Research, monthly, ISSN 1918-3003 (print), 1918-3011 (online), published by Elmer Press Inc.     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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