Journal of Clinical Medicine Research

Frequency: Monthly
Journal Access:
Open Access
ISSN-print: 1918-3003
ISSN-online: 1918-3011
Journal scope: All disciplines of clinical medicine, medical research and clinical practice, preventive medicine, epidemiology, nursing, and healthcare research. Submissions include interventional trials reports, evidence-based medical research reports, meta-analyses, observational studies, retrospective and prospective studies, and other clinical studies.
Indexed and covered: PubMed, PubMed Central, Chemical Abstract (CA), Directory of Open Access Journals (DOAJ), EBSCO, Worldcat, JournalTOCs, Google, Google Scholar, Thomson Reuters Links Journal Title List.
Journal archiving and digital preservation: Portico


  • Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation

    The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt.

  • LDLR C1725T Gene Polymorphism Frequency in Type 2 Diabetes Mellitus Patients With Dyslipidemia

    Dyslipidemia has a substantial role in the development of cardiovascular diseases in patients with type 2 diabetes mellitus (T2DM). Determining the genetic profile of T2DM patients with dyslipidemia is important in order to reduce the risk of microvascular and macrovascular complications. Low-density lipoprotein receptor (LDLR) plays a critical role in plasma lipoprotein hemostasis.

  • Hypertension Prevalence, Awareness and Blood Pressure Control in Matao, Brazil: A Pilot Study in Partnership With the Brazilian Family Health Strategy Program

    Around 30% of Brazilian population is hypertensive. Brazilian’s Family Health Strategy (FHS) is a community-based approach to provide primary health care and control chronic disease as hypertension. The aims of this pilot study were to study hypertension prevalence and awareness and to analyze the feasibility of FHS program with community healthy agents (CHA)...

  • Oxidative Stress Measurement and Prediction of Epileptic Seizure in Children and Adults With Severe Motor and Intellectual Disabilities

    The medical care of severe motor and intellectual disabilities (SMID) depends on the empirical medical care. Epileptic seizure specific to SMID is difficult to suppress using anti-epileptic drugs, and its tendency to persist for long periods poses an issue.

  • An Insight Into the Immunologic Events and Risk Assessment in Renal Transplantation

    Organ transplantation has always been considered to be the optimal therapeutic intervention in patients with end-stage organ failure. In the US, approximately 615,000 patients are diagnosed with end-stage renal disease and less than 30% have received a kidney transplant.

  • Systemic Immunosuppression in High-Risk Penetrating Keratoplasty: A Systematic Review

    Cornea transplantation has a high success rate and typically only requires topical immunomodulation. However, in high-risk cases, systemic immunosuppression can be used. We conducted a systematic review on the efficacy and side effects of systemic immunosuppression for high-risk cornea transplantation.

  • Morphological and Morphometrical Study of the Human Ossicular Chain: A Review of the Literature and a Meta-Analysis of Experience Over 50 Years

    We reviewed the whole literature that is available online regarding the human ossicular chain from an anatomist perspective and correlated the data from all the papers that showed any relevance.







Increased Hematocrit During Sodium-Glucose Cotransporter 2 Inhibitor Therapy Indicates Recovery of Tubulointerstitial Function in Diabetic Kidneys
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been attracting attention for cardiovascular as well as antidiabetic effects since the results of the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME Trial) were reported. Vol. 8 | No. 12 | 2016 Full Text

Effects of Helicobacter pylori Eradication on the Platelet Count in Hepatitis C Virus-Infected Patients
Helicobacter pylori (H. pylori) infection is associated with a low platelet count in patients with immune thrombocytopenic purpura (ITP). While eradication of H. pylori is an established therapy for increasing the platelet count in ITP patients, it is unclear whether or not eradication will similarly affect the platelet counts in patients with chronic liver diseases (CLDs). Vol. 8 | No. 12 | 2016 Full Text

Image of the Issue

Successful Closure of a Ventricular Septal Defect Using a Novel Non-Prosthesis Touching Technique Following Mechanical Aortic Valve Replacement
Percutaneous intervention is preferred over reoperation for the treatment of iatrogenic membranous ventricular septal defects (VSDs). During the standard percutaneous procedure, an arterio-venous loop is used for occluder deployment, entailing the risk of device impingement on the prosthetic aortic valve, which may cause serious complications or even death. Vol. 8 | No. 12 | 2016 Full Text

Video Report

Isolated Right Ventricular Dilated Cardiomyopathy: An Early Diagnosis
Because of an incomplete right bundle branch block, a severe right ventricular dilatation with no left ventricular cardiomyopathy was found in a 44-year-old man. Magnetic resonance and transesophageal echocardiography confirmed the finding and these tests also failed to find any potential cause. A pulmonary hemodynamic study and a coronary angiography were strictly normal. Vol. 7 | No. 10 | 2015 Full Text

Current Issue

Past Issues

Vol. 8, No. 12, Dec 2016

Table of Contents


Why Physicians Should Look at the Mouths of Their Patients Abstract HTML PDF
Luciano Alberto de Castro, Joao Gabriel Leite de Castro, Jayanne Silva de Alcantara, Divino Alves Garcia Junior, Caio Santana Novaes Romeu, Itagores Hoffman II Lopes Sousa Coutinho 841-843


Increased Hematocrit During Sodium-Glucose Cotransporter 2 Inhibitor Therapy Indicates Recovery of Tubulointerstitial Function in Diabetic Kidneys Abstract HTML PDF
Motoaki Sano, Makoto Takei, Yasuyuki Shiraishi, Yoshihiko Suzuki 844-847
Exercise Intervention for Anti-Sarcopenia in Community-Dwelling Older People Abstract HTML PDF
Ryo Miyazaki, Taro Takeshima, Kazuhiko Kotani 848-853

Original Article

Effects of Helicobacter pylori Eradication on the Platelet Count in Hepatitis C Virus-Infected Patients Abstract HTML PDF
Tomoyuki Takashima, Hirayuki Enomoto, Yoshinori Iwata, Hiroki Nishikawa, Kazunori Yoh, Kunihiro Hasegawa, Chikage Nakano, Yukihisa Yuri, Noriko Ishii, Yuho Miyamoto, Ryo Takata, Takashi Nishimura, Akio Ishii, Yoshiyuki Sakai, Nobuhiro Aizawa, Naoto Ikeda, Hiroko Iijima, Shuhei Nishiguchi 854-858
Clinical Impact of Blood Culture Results in Acutely Ill Hospitalized Adult Patients With Cystic Fibrosis Abstract HTML PDF
Robert J. Vender, Robert L. Vender 859-862
Effect of L-Carnitine in Patients With Liver Cirrhosis on Energy Metabolism Using Indirect Calorimetry: A Pilot Study Abstract HTML PDF
Yoshiyuki Sakai, Hiroki Nishikawa, Hirayuki Enomoto, Kazunori Yoh, Yoshinori Iwata, Kunihiro Hasegawa, Chikage Nakano, Kyohei Kishino, Yoshihiro Shimono, Ryo Takata, Takashi Nishimura, Nobuhiro Aizawa, Naoto Ikeda, Tomoyuki Takashima, Akio Ishii, Hiroko Iijima, Shuhei Nishiguchi 863-869
High Prevalence of Toxoplasma gondii Infection in Miners: A Case-Control Study in Rural Durango, Mexico Abstract HTML PDF
Cosme Alvarado-Esquivel, Sandy Janet Pacheco-Vega, Jesus Hernandez-Tinoco, Luis Omar Berumen-Segovia, Luis Francisco Sanchez-Anguiano, Sergio Estrada-Martinez, Ada Agustina Sandoval-Carrillo, Jose Manuel Salas-Pacheco, Oliver Liesenfeld, Elizabeth Irasema Antuna-Salcido 870-877
The Effects of Ramelteon on Glucose Metabolism and Sleep Quality in Type 2 Diabetic Patients With Insomnia: A Pilot Prospective Randomized Controlled Trial Abstract HTML PDF
Tetsuji Tsunoda, Masayo Yamada, Tomoaki Akiyama, Taichi Minami, Taishi Yoshii, Yoshinobu Kondo, Shinobu Satoh, Yasuo Terauchi 878-887
Efficacy and Safety of a Single-Pill Fixed-Dose Combination of Azilsartan and Amlodipine Abstract HTML PDF
Kota Motozato, Shin-ichiro Miura, Yuhei Shiga, Takaaki Kusumoto, Keijiro Saku 888-892
Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation Abstract HTML PDF
Santosh Kumar Sinha, Vikas Mishra, Karandeep Singh, Mohammad Asif, Mohit Sachan, Ashutosh Kumar, Mukesh Jitendra Jha, Dibbendhu Khanra, Avinash Kumar Singh, Shravan Singh, Mahamdula Razi, Ramesh Thakur, Umeshwar Pandey, Chandra Mohan Varma 893-898
Evaluation of the Antithrombotic Effects of Rivaroxaban and Apixaban Using the Total Thrombus-Formation Analysis System®: In Vitro and Ex Vivo Studies Abstract HTML PDF
Hidekazu Sugihara, Yoshiaki Idemoto, Takashi Kuwano, Yoshihisa Nagata, Joji Morii, Makoto Sugihara, Masahiro Ogawa, Shin-ichiro Miura, Keijiro Saku 899-907
Antioxidant and Renoprotective Effects of Mushroom Extract: Implication in Prevention of Nephrolithiasis Abstract HTML PDF
Ariel Schulman, Matthew Chaimowitz, Muhammad Choudhury, Majid Eshghi, Sensuke Konno 908-915

Short Communication

Propionibacterium acnes: Time-to-Positivity in Standard Bacterial Culture From Different Anatomical Sites Abstract HTML PDF
Rasha Abdulmassih, Jina Makadia, James Como, Michelle Paulson, Zaw Min, Nitin Bhanot 916-918

Case Report

Ketoacidosis in a Non-Diabetic Adult With Chronic EtOH Consumption Abstract HTML PDF
Catherine-Audrey Boutin, Mikhael Laskine 919-920
Fulminant Hepatic Failure Secondary to Herpes Hepatitis in a Patient With Myasthenia Crisis: An Elusive Diagnosis Abstract HTML PDF
Harish Patel, Hassan Tariq, Vinaya Gaduputi, Trupti Vakde, Jasbir Makker, Myrta Daniel 921-924
Successful Closure of a Ventricular Septal Defect Using a Novel Non-Prosthesis Touching Technique Following Mechanical Aortic Valve Replacement Abstract HTML PDF
Xinghua Gu, Hourong Sun, Lei Zhang, Changjing Qi, Kejie Cai, Xiquan Zhang 925-927




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Journal of Clinical Medicine Research, monthly, ISSN 1918-3003 (print), 1918-3011 (online), published by Elmer Press Inc.     
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