Journal of Clinical Medicine Research

Frequency: Monthly
Editor-in-Chief: Richard Liu, MD, Elmer Press, Toronto, Canada
Journal Access: Open Access
ISSN-print: 1918-3003
ISSN-online: 1918-3011
Journal scope: Multi-discipline of clinical medicine, medical research and clinical practice, preventive medicine, epidemiology, nursing, and healthcare research, clinically focused, evidence-based medicine.
Indexed and covered: PubMed, PubMed Central, Chemical Abstract (CA), EBSCO, Worldcat, JournalTOCs, Google, Google Scholar, Clarivate Analytics Links- Journal Title List.

Journal archiving and digital preservation:


  • Effects of Repaglinide Versus Glimepiride on 1,5-Anhydroglucutol and Glycated Hemoglobin Levels in Japanese Patients With Type 2 Diabetes

    Postprandial hyperglycemia is a well-known risk factor for cardiovascular disease. We prospectively examined the effects of repaglinide on postprandial hyperglycemia in patients with type 2 diabetes. During this 24-week, single-arm, prospective study, we enrolled 10 patients with type 2 diabetes who were previously being administered glimepiride (0.5 or 1 mg/day) and switched it with repaglinide (0.75 or 1.5 mg/day).

  • Does Red Cell Distribution Width Predict Outcome in Traumatic Brain Injury: Comparison to Corticosteroid Randomization After Significant Head Injury

    Traumatic brain injury (TBI) is a leading cause of death and disability. The role of red cell distribution width (RDW) as a prognostic biomarker for outcome in TBI patients is unknown. Based on the corticosteroid randomization after significant head injury (CRASH) trial database, a prognosis calculator (CRASH) has been developed for outcome prediction in TBI.

  • A Multiple Treatment Comparison of Eleven Disease-Modifying Drugs Used for Multiple Sclerosis

    Several disease-modifying drug therapies are available for the treatment of multiple sclerosis (MS). To ensure the most appropriate MS management, we assessed the effectiveness and cost-effectiveness of the disease-modifying medicines used for MS.

  • Pancreatic Involvement in Inflammatory Bowel Disease

    Inflammatory bowel disease (IBD) is a multisystemic disease, and pancreatic manifestations of IBD are not uncommon. The incidence of several pancreatic diseases in Crohn’s disease and ulcerative colitis is more frequent compared to the general population.

  • Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation

    The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt.

  • Assessment of Salivary Nitric Oxide Levels in Elite University Athletes in Japan: Findings From a Cross Sectional Study Design

    High-intensity exercise affects the level of salivary nitric oxide (NO) with an impact on oxidative stress such as a reactive nitrogen-oxide species. However, in athletes with high-intensity training, the relationship between salivary NO levels and oxidative stress is yet to be clear. Additionally, the association of salivary NO levels and the common health disorders of athletes is unknown.







Specific Features of Patients With Inflammatory Bowel Disease and Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic and progressive disease of the biliary tract. PSC is strongly associated with inflammatory bowel disease (IBD), mainly with ulcerative colitis, and most PSC patients have underlying IBD. The pathophysiological interactions between IBD and PSC are unclear, although it seems that the patients with IBD and PSC have a distinct phenotype. Full Text

Cytoskeletal Tropomyosin as a Biomarker in Clostridium difficile Infection
Clostridium difficile infection (CDI) is a significant health concern worldwide and is recognized as the most frequent etiologic agent of healthcare-associated infectious diarrhea in hospitalized adult patients. For the last two decades, CDI has re-emerged in healthcare facilities with nearly a 10-fold increase in mortality. Full Text

Image of the Issue

Massive Hemoptysis Due to the Rupture of Thoracic Aortic Aneurysm Caused by Leukemic Cell Infiltration in a Patient With Chronic Myelomonocytic Leukemia
Hemoptysis is occasionally experienced in patients with hematological malignancies who have respiratory tract infection and severe thrombocytopenia. Thrombocytopenia due to hematological disease is one cause of hemoptysis. Full Text

Video Report

Isolated Right Ventricular Dilated Cardiomyopathy: An Early Diagnosis
Because of an incomplete right bundle branch block, a severe right ventricular dilatation with no left ventricular cardiomyopathy was found in a 44-year-old man. Magnetic resonance and transesophageal echocardiography confirmed the finding and these tests also failed to find any potential cause. A pulmonary hemodynamic study and a coronary angiography were strictly normal. Full Text

Current Issue

Past Issues

Vol. 11, No. 3, Mar 2019

Table of Contents

Original Article

Status of Emergency Department Seventy-Two Hour Return Visits Among Homeless Patients Abstract HTML PDF
Heidi Knowles, Charles Huggins, Richard D. Robinson, Rosalia Mbugua, Jessica Laureano-Phillips, Shrunjal M. Trivedi, Jessica Kirby, Nestor R. Zenarosa, Hao Wang 157-164
Association of Oral Function With Long-Term Participation in Community-Based Oral Exercise Programs in Older Japanese Women: A Cross-Sectional Study Abstract HTML PDF
Sanae Miyoshi, Hideo Shigeishi, Eri Fukada, Maki Nosou, Hideaki Amano, Masaru Sugiyama 165-170
Hyperbilirubinemia as a Predictor of Appendiceal Perforation: A Systematic Review and Diagnostic Test Meta-Analysis Abstract HTML PDF
Paschalis Gavriilidis, Nicola de’Angelis, John Evans, Salomone Di Saverio, Peter Kang 171-178
Relationship of Salivary Occult Blood With General and Oral Health Status in Employees of a Japanese Department Store Abstract HTML PDF
Kazushi Segawa, Hideo Shigeishi, Munehito Fujii, Kazuki Noumi, Fuminori Yamanaka, Katsumi Kamikawa, Shinsuke Arakawa, Masaru Sugiyama 179-187
Preoperative Depressive Mood of Patients With Esophageal Cancer Might Delay Recovery From Operation-Related Malnutrition Abstract HTML PDF
Yoshihiro Nakamura, Chika Momoki, Genya Okada, Yoshinari Matsumoto, Yoko Yasui, Daiki Habu, Yasunori Matsuda, Shigeru Lee, Harushi Osugi 188-195
Human Papillomavirus Infection in Female Sex Workers: A Case Control Study Abstract HTML PDF
Nadia Velazquez-Hernandez, Luis Francisco Sanchez-Anguiano, Fernando Martin Guerra-Infante, Marisela Aguilar-Duran, Alma Rosa Perez-Alamos, Sergio Estrada-Martinez, Jose Antonio Navarrete-Flores, Ada Agustina Sandoval-Carrillo, Elizabeth Irasema Antuna-Salcido, Jesus Hernandez-Tinoco, Cosme Alvarado-Esquivel 196-201
Effect of Switching to Azilsartan From Fixed-Dose Combination of an Angiotensin II Receptor Blocker and Calcium Channel Blocker or a Thiazide in Patients With Hypertension Abstract HTML PDF
Toru Miyoshi, Go Onoue, Hiroshi Ito 202-207
A Retrospective Study of Kidney Stone Recurrence in Adults Abstract HTML PDF
Jianfeng Zeng, Shanyun Wang, Liang Zhong, Zhifeng Huang, Ye Zeng, Dongxiang Zheng, Weiwei Zou, Haibiao Lai 208-212
Risk Factors of Hypoglycemic Encephalopathy and Prolonged Hypoglycemia in Patients With Severe Hypoglycemia Abstract HTML PDF Suppl1 Suppl2
Rika Saikawa, Hodaka Yamada, Daisuke Suzuki, Misato Amamoto, Yuko Matsumoto, Shunsuke Funazaki, Masashi Yoshida, Hideo Toyoshima, Kazuo Hara 213-218

Short Communication

Liraglutide Reduces Visceral and Intrahepatic Fat Without Significant Loss of Muscle Mass in Obese Patients With Type 2 Diabetes: A Prospective Case Series Abstract HTML PDF
Satoshi Ishii, Yoshio Nagai, Yukiyoshi Sada, Hisashi Fukuda, Yuta Nakamura, Ren Matsuba, Tomoko Nakagawa, Hiroyuki Kato, Yasushi Tanaka 219-224




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Journal of Clinical Medicine Research, monthly, ISSN 1918-3003 (print), 1918-3011 (online), published by Elmer Press Inc.        
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