Journal of Clinical Medicine Research

Kei Nakajima, Professor, MD, PhD, School of Nutrition and Dietetics, Faculty of Health and Social Services, Kanagawa University of Human Services, Kanagawa, Japan

Frequency: Monthly
Journal Access: Open Access
ISSN-print: 1918-3003
ISSN-online: 1918-3011
Indexed and covered: PubMed, PubMed Central, Chemical Abstract (CA), EBSCO, Worldcat, JournalTOCs, Google, Google Scholar, Clarivate Analytics Links- Journal Title List.

Journal archiving and digital preservation:


  • Effects of Tofogliflozin on Cardiac Function in Elderly Patients With Diabetes Mellitus

    Patients with type 2 diabetes mellitus (T2DM) are at increased risk for impairments in diastolic relaxation and heart failure with preserved ejection fraction (EF). Recent clinical data suggest that several sodium glucose transporter-2 (SGLT2) inhibitors are found to reduce cardiovascular disease (CVD) events in elderly diabetic patients, but the effect of tofogliflozin, one of the SGLT2 inhibitors, on CVD is unknown.

  • Does Red Cell Distribution Width Predict Outcome in Traumatic Brain Injury: Comparison to Corticosteroid Randomization After Significant Head Injury

    Traumatic brain injury (TBI) is a leading cause of death and disability. The role of red cell distribution width (RDW) as a prognostic biomarker for outcome in TBI patients is unknown. Based on the corticosteroid randomization after significant head injury (CRASH) trial database, a prognosis calculator (CRASH) has been developed for outcome prediction in TBI.

  • A Multiple Treatment Comparison of Eleven Disease-Modifying Drugs Used for Multiple Sclerosis

    Several disease-modifying drug therapies are available for the treatment of multiple sclerosis (MS). To ensure the most appropriate MS management, we assessed the effectiveness and cost-effectiveness of the disease-modifying medicines used for MS.

  • Risk of Stroke in Patients With Patent Foramen Ovale Who Had Pulmonary Embolism

    The presence of patent foramen ovale (PFO) alone does not increase the risk of ischemic stroke. Several prospective studies with a small number of patients have shown that the risk of ischemic stroke is higher in patients with PFO and pulmonary embolism (PE).

  • Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation

    The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt.

  • Assessment of Salivary Nitric Oxide Levels in Elite University Athletes in Japan: Findings From a Cross Sectional Study Design

    High-intensity exercise affects the level of salivary nitric oxide (NO) with an impact on oxidative stress such as a reactive nitrogen-oxide species. However, in athletes with high-intensity training, the relationship between salivary NO levels and oxidative stress is yet to be clear. Additionally, the association of salivary NO levels and the common health disorders of athletes is unknown.







Serious Conditions in COVID-19 Accompanied With a Feature of Metabolic Syndrome
At the time of this writing, coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain of coronavirus has reached pandemic levels, threatening human life and limiting activity worldwide. Urgent COVID-19 studies are required to confirm the association between serious condition and obesity and diabetes, investigate the fundamental features of MetS in terms of causality, and explore potential treatments for the multitude of patients all around the world. Full Text

COVID-19, Modern Pandemic: A Systematic Review From Front-Line Health Care Providers’ Perspective
Coronavirus disease 2019 (COVID-19) caused infection in 168,000 cases worldwide in about 148 countries and killed more than 6,610 people around the world as of March 16, 2020, as per the World Health Organization (WHO). Compared to severe acute respiratory syndrome and Middle East respiratory syndrome, there is the rapid transmission, long incubation period, and disease containment is becoming extremely difficult. Full Text

Image of the Issue

A Comprehensive Approach Is Vital for Diagnosing COVID-19: A Case of False Negative
We present a case of COVID-19 patient whose reverse transcription-polymerase chain reaction (RT-PCR) initially was false negative and later turned positive, which will stress the importance of a comprehensive approach while evaluating a patient with a differential of COVID-19. Full Text

Combat the COVID-19

Let's Combat COVID-19 Pandemic Together
The COVID-19 outbreak presents the unprecedented challenge for world public and medical practitioners and health care providers. The Elmer Press Inc is herein to participate the combating COVID-19 through all possible efforts, as a clinical medicine publisher, we would facilitate the rapid and effective communication of management of this pandemic, we will consider submissions related to all aspects of this disease, including prevention, basic viral research, epidemiology, treatment, vaccine, fast screening, diagnosis, prognosis, etc. We will process such manuscripts in priority and publish them ASAP after peer-reviewed and accepted.

Current Issue

Past Issues

Vol. 12, No. 6, Jun 2020

Table of Contents


Opportunities and Limitations in the Study of Transient Takotsubo Syndrome in Animal Models Abstract HTML PDF
Paolo Angelini, Maria T. Gamero 325-328


Medical Management of COVID-19: Evidence and Experience Abstract HTML PDF Suppl1
Subhasish Bose, Sreedhar Adapa, Narothama Reddy Aeddula, Sasmit Roy, Deepak Nandikanti, Phani Mohan Vupadhyayula, Srikanth Naramala, Vijay Gayam, Vijayadershan Muppidi, Venu Madhav Konala 329-343
A Scoping Review on Clinical Trials of Pain Reduction With Cannabis Administration in Adults Abstract HTML PDF Suppl1 Suppl2
Reham Haleem, Robert Wright 344-351
COVID-19 Pandemic Causing Acute Kidney Injury and Impact on Patients With Chronic Kidney Disease and Renal Transplantation Abstract HTML PDF
Sreedhar Adapa, Avantika Chenna, Mamtha Balla, Ganesh Prasad Merugu, Narayana Murty Koduri, Subba Rao Daggubati, Vijay Gayam, Srikanth Naramala, Venu Madhav Konala 352-361

Original Article

Outpatient Management of Bronchial Asthma: A Comparative Analysis Between Guideline-Directed Management and Usual Management Abstract HTML PDF
Jeyanthan Jayakumaran, Krystal Hunter, Satyajeet Roy 362-368
Purifying selection in HIV-1 pol gene in perinatally HIV-1-infected children harboring discordant immunological response and virological nonresponse to long-term antiretroviral therapy Abstract HTML PDF
Ralph-Sydney Mboumba Bouassa, Helene Pere, Christian Diamant Mossoro-Kpinde, Pierre Roques, Jean Chrysostome Gody, Sandrine Moussa, David Veyer, Gerard Gresenguet, Charlotte Charpentier, Mohammad-Ali Jenabian, Joel Fleury Djoba Siawaya, Laurent Belec 369-376
Associations Between Cannabis Use, Abdominal Fat Phenotypes and Insulin Traits Abstract HTML PDF
Charlotte E. Stuart, Juyeon Ko, Gisselle C. Alarcon Ramos, Andre E. Modesto, Jaelim Cho, Maxim S. Petrov 377-388

Letter to the Editor

A Significance of High Prevalence of Diabetes and Hypertension in Severe COVID-19 Patients Abstract HTML PDF
Hidekatsu Yanai 389-392





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Journal of Clinical Medicine Research, monthly, ISSN 1918-3003 (print), 1918-3011 (online), published by Elmer Press Inc.            
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