Vulvovestibular Syndrome and Vaginal Microbiome: A Simple Evaluation

Maria Vadala, Christian Testa, Laura Coda, Stefania Angioletti, Rosanna Giuberti, Carmen Laurino, Beniamino Palmieri


Background: The vulvovestibular syndrome (VVS) is a chronic, inflammatory, multifactorial, chronic inflammation of the female urogenital access.

Methods: The aim of this anecdotal, observational, retrospective, case-control study was to comparatively evaluate the most common bacterial strains (Lactobacillus spp., Klebsiella spp., Gardnerella spp., and Streptococcus spp.) and fungi (Candida spp., Pennicillum spp., and Aspergillus spp.) in vulvodinic women, and in women without gynecological symptoms (control group).

Results: We found that vulvodinic patients had statistically lower Lactobacilli and higher total Fungi concentration.

Conclusions: Our preliminary study is useful to further clarify the etiopathology of vulvodynia and suggest new therapeutic strategies for approaching the VVS.

J Clin Med Res. 2018;10(9):688-692


VVS; Vulvodinic; Lactobacilli; Fungi; Bacteria; Women

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