Journal of Clinical Medicine Research

Frequency: Monthly
Editor-in-Chief: Richard Liu, MD, Elmer Press, Toronto, Canada
Journal Access: Open Access
ISSN-print: 1918-3003
ISSN-online: 1918-3011
Journal scope: Multi-discipline of clinical medicine, medical research and clinical practice, preventive medicine, epidemiology, nursing, and healthcare research, clinically focused, evidence-based medicine.
Indexed and covered: PubMed, PubMed Central, Chemical Abstract (CA), EBSCO, Worldcat, JournalTOCs, Google, Google Scholar, Clarivate Analytics Links- Journal Title List.

Journal archiving and digital preservation:


  • Effects of Repaglinide Versus Glimepiride on 1,5-Anhydroglucutol and Glycated Hemoglobin Levels in Japanese Patients With Type 2 Diabetes

    Postprandial hyperglycemia is a well-known risk factor for cardiovascular disease. We prospectively examined the effects of repaglinide on postprandial hyperglycemia in patients with type 2 diabetes. During this 24-week, single-arm, prospective study, we enrolled 10 patients with type 2 diabetes who were previously being administered glimepiride (0.5 or 1 mg/day) and switched it with repaglinide (0.75 or 1.5 mg/day).

  • Does Red Cell Distribution Width Predict Outcome in Traumatic Brain Injury: Comparison to Corticosteroid Randomization After Significant Head Injury

    Traumatic brain injury (TBI) is a leading cause of death and disability. The role of red cell distribution width (RDW) as a prognostic biomarker for outcome in TBI patients is unknown. Based on the corticosteroid randomization after significant head injury (CRASH) trial database, a prognosis calculator (CRASH) has been developed for outcome prediction in TBI.

  • A Multiple Treatment Comparison of Eleven Disease-Modifying Drugs Used for Multiple Sclerosis

    Several disease-modifying drug therapies are available for the treatment of multiple sclerosis (MS). To ensure the most appropriate MS management, we assessed the effectiveness and cost-effectiveness of the disease-modifying medicines used for MS.

  • Pancreatic Involvement in Inflammatory Bowel Disease

    Inflammatory bowel disease (IBD) is a multisystemic disease, and pancreatic manifestations of IBD are not uncommon. The incidence of several pancreatic diseases in Crohn’s disease and ulcerative colitis is more frequent compared to the general population.

  • Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation

    The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt.

  • Assessment of Salivary Nitric Oxide Levels in Elite University Athletes in Japan: Findings From a Cross Sectional Study Design

    High-intensity exercise affects the level of salivary nitric oxide (NO) with an impact on oxidative stress such as a reactive nitrogen-oxide species. However, in athletes with high-intensity training, the relationship between salivary NO levels and oxidative stress is yet to be clear. Additionally, the association of salivary NO levels and the common health disorders of athletes is unknown.







Specific Features of Patients With Inflammatory Bowel Disease and Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic and progressive disease of the biliary tract. PSC is strongly associated with inflammatory bowel disease (IBD), mainly with ulcerative colitis, and most PSC patients have underlying IBD. The pathophysiological interactions between IBD and PSC are unclear, although it seems that the patients with IBD and PSC have a distinct phenotype. Full Text

Cytoskeletal Tropomyosin as a Biomarker in Clostridium difficile Infection
Clostridium difficile infection (CDI) is a significant health concern worldwide and is recognized as the most frequent etiologic agent of healthcare-associated infectious diarrhea in hospitalized adult patients. For the last two decades, CDI has re-emerged in healthcare facilities with nearly a 10-fold increase in mortality. Full Text

Image of the Issue

Massive Hemoptysis Due to the Rupture of Thoracic Aortic Aneurysm Caused by Leukemic Cell Infiltration in a Patient With Chronic Myelomonocytic Leukemia
Hemoptysis is occasionally experienced in patients with hematological malignancies who have respiratory tract infection and severe thrombocytopenia. Thrombocytopenia due to hematological disease is one cause of hemoptysis. Full Text

Video Report

Isolated Right Ventricular Dilated Cardiomyopathy: An Early Diagnosis
Because of an incomplete right bundle branch block, a severe right ventricular dilatation with no left ventricular cardiomyopathy was found in a 44-year-old man. Magnetic resonance and transesophageal echocardiography confirmed the finding and these tests also failed to find any potential cause. A pulmonary hemodynamic study and a coronary angiography were strictly normal. Full Text

Current Issue

Past Issues

Vol. 11, No. 4, Apr 2019

Table of Contents


Adverse Effects of Immune Checkpoint Inhibitors (Programmed Death-1 Inhibitors and Cytotoxic T-Lymphocyte-Associated Protein-4 Inhibitors): Results of a Retrospective Study Abstract HTML PDF
Ravneet Bajwa, Anmol Cheema, Taimoor Khan, Alireza Amirpour, Anju Paul, Saira Chaughtai, Shrinil Patel, Tejas Patel, Joshua Bramson, Varsha Gupta, Michael Levitt, Arif Asif, Mohammad A. Hossain 225-236
Peripheral Inserted Central Catheter Use and Related Infections in Clinical Practice: A Literature Update Abstract HTML PDF
Dimitrios Velissaris, Vasileios Karamouzos, Maria Lagadinou, Charalampos Pierrakos, Markos Marangos 237-246

Original Article

Association Between the Use of Thiazide Diuretics and the Risk of Skin Cancers: A Meta-Analysis of Observational Studies Abstract HTML PDF Suppl1 Suppl2 Suppl3
Doosup Shin, Eun Sun Lee, Joonseok Kim, Lucy Guerra, Dayan Naik, Xavier Prida 247-255
Long-Term Efficacy, Safety, and Tolerability of Modified Intravesical Oxybutynin Chloride for Neurogenic Bladder in Children Abstract HTML PDF
Masashi Honda, Yusuke Kimura, Panagiota Tsounapi, Katsuya Hikita, Motoaki Saito, Atsushi Takenaka 256-260
Sleep Quality in Patients With Type 2 Diabetes Mellitus Abstract HTML PDF
Safa Barakat, Mousa Abujbara, Radwan Banimustafa, Anwar Batieha, Kamel Ajlouni 261-266
Renoprotective Effects of Additional SGLT2 inhibitor Therapy in Patients With Type 2 Diabetes Mellitus and Chronic Kidney Disease Stages 3b-4: A Real World Report From A Japanese Specialized Diabetes Care Center Abstract HTML PDF
Seigo Sugiyama, Hideaki Jinnouchi, Akira Yoshida, Kunio Hieshima, Noboru Kurinami, Katsunori Jinnouchi, Motoko Tanaka, Tomoko Suzuki, Fumio Miyamoto, Keizo Kajiwara, Tomio Jinnouchi 267-274
Prevalence of Solid Neoplasms Diagnosed Between the Years of 2011 to 2016 and Oncologically Treated at the University Hospital of Santa Maria Abstract HTML PDF
Fernando Borges da Silva, Marcelo Binato, Juliano Tonezer da Silva, Clandio Timm Marques, Tiango Aguiar Ribeiro 275-282
Nutritional Support of Very Low Birth Weight Infants in a Tertiary Center in a Developing Country Abstract HTML PDF
Manar Al-lawama, Haneen Abu Alrous, Haitham Alkhatib, Abdelkareem Alrafaeh, Zaid Wakileh, Bushra Alawaisheh, Aseel Saadeh, Jumana Sharab, Eman Badran, Abla Albsoul-Younes 283-288
Associations of Pericardial Fat Area Determined by Routine Chest Computed Tomography With Coronary Risk Factors and Coronary Artery Disease Abstract HTML PDF
Reo Yoshikawa, Hidekatsu Yanai, Sumie Moriyama, Narihiro Furugaki 289-296

Short Communication

Differing Effect of the Sodium-Glucose Cotransporter 2 Inhibitor Ipragliflozin on the Decrease of Fat Mass vs. Lean Mass in Patients With or Without Metformin Therapy Abstract HTML PDF
Yoshio Nagai, Hisashi Fukuda, Shin Kawanabe, Tomoko Nakagawa, Akio Ohta, Yasushi Tanaka 297-300

Case Report

HIV-Infected Patient Diagnosed With Osteomedullary and Hepatic Syphilis on Positron Emission Tomography: A Case Report Abstract HTML PDF
Antoine Desilets, Frederic Arsenault, Mikhael Laskine 301-304
Complete Occlusion of Bilateral Internal Carotid Artery in a Marijuana Smoker: A Case Report Abstract HTML PDF
Dikshya Sharma, Udip Dahal, Edward yu 305-308

Letter to the Editor

Secondary Prevention of Atrial Fibrillation: Is It Worth Doing? Abstract HTML PDF
Renato De Vecchis 309




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Journal of Clinical Medicine Research, monthly, ISSN 1918-3003 (print), 1918-3011 (online), published by Elmer Press Inc.        
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
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