Elmer Press, Medical and Scientific Publishing
Journal of
Clinical Medicine Research

Frequency: Bimonthly, Open Access
ISSN-print: 1918-3003
ISSN-online: 1918-3011
Journal scope: All disciplines of clinical medicine, medical research and clinical practice, preventive medicine, epidemiology, nursing, and healthcare research

Indexed and covered: PubMed, PubMed Central, Chemical Abstract (CA), Directory of Open Access Journals (DOAJ), Open J-Gate, JournalSeek, Google Scholar

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Featured Article

Nephrotoxin-Induced Renal Cell Injury Involving Biochemical Alterations and Its Prevention With Antioxidant
Although nephrotoxic agents or nephrotoxins are known to induce acute renal cell injury, their cytotoxic action is not fully elucidated. It is thus crucial to explore such a cytotoxic mechanism and the increasing volume of reports indicated a significant involvement of oxidative stress. To test this possibility, we investigated if a nephrotoxin would exert oxidative stress, leading to renal cell injury accompanied by certain biochemical alterations. We also examined if specific antioxidant might help prevent such oxidative cell injury. These studies may then help establish a prophylactic or preventive modality for renal cell injury induced by nephrotoxins. Full Text

Image of the Issue

Metastases From Nested Variant Urothelial Carcinoma of the Urinary Bladder in Pancreatic Allograft Mimicking Graft Rejection
While not an uncommon tumor, urothelial carcinoma of the urinary bladder is rare in bladders draining pancreatic allografts. A case of urothelial carcinoma directly involving a pancreatic allograft with metastasis that occurred in a 49-year-old pancreas and kidney transplant recipient is described. Her initial clinical presentation and findings of CT scan of the abdomen suggested pancreatitis with features worrisome for rejection. A biopsy of her pancreatic allograft contained poorly differentiated carcinoma and cystoscopic biopsy disclosed an invasive high grade urothelial carcinoma arising in the background of extensive urothelial carcinoma in situ. Full Text