| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website https://www.jocmr.org |
Original Article
Volume 13, Number 8, August 2021, pages 420-424
Perinatal Transmission and Clinical Outcomes of Neonates Born to SARS-CoV-2-Positive Mothers
Table
| Characteristics | All newborns (n = 130) | SARS-CoV-2-positive (n = 16) | SARS-CoV-2-negative (n = 112) | P value |
|---|---|---|---|---|
| SARS-CoV-2: severe acute respiratory syndrome coronavirus 2; SD: standard deviation; ICU: intensive care unit. | ||||
| Gestational age (weeks) | 36 (29 - 41) | 35 (3) | 37 (2.5) | 0.004 |
| Gestational age < 34 weeks | 24 (18.46%) | 5 (31.25%) | 19 (17.0%) | 0.180 |
| Birth weight (g) (mean ± SD) | 2,900 ± 653 | 2,400 ± 748 | 2,790 ± 627 | 0.025 |
| Cesarean section | 81 (66%) | 10 (62%) | 71 (62%) | 1.000 |
| Male sex | 58 (45%) | 6 (37.5%) | 51 (45.53%) | 0.596 |
| Apgar scores (mean) | ||||
| First minute | 8 | 7 | 8 | |
| Fifth minute | 9 | 9 | 9 | |
| Neonatal ICU admission | 50 (38%) | 11 (68%) | 39 (34%) | 0.014 |
| Bradycardia | 5 (3.85%) | 3 (18.8%) | 2 (1.8%) | 0.014 |
| Respiratory support | 33 (25.38%) | 7 (43%) | 26 (22%) | 0.122 |
| Non-invasive | 29 | 5 | 24 | 0.036 |
| Invasive | 4 | 2 | 2 | 0.076 |
| Surfactant therapy | 5 (3.85%) | 4 (25%) | 1 (0.9) | 0.001 |
| Hyperbilirubinemia | 18 (13.85%) | 6 (37%) | 12 (10%) | 0.011 |
| High C-reactive protein | 7 (5.4%) | 3 (18.8%) | 4 (3.6%) | 0.042 |
| Received antibiotics in the first 48 h with negative cultures | 30 (23.1%) | 9 (56%) | 21 (18.8%) | 0.003 |
| Breastfeeding | 60 (46.1%) | 8 (50%) | 52 (45%) | 0.796 |
| Mortality | 3 (2.3%) | 1 (6%) | 2 (1.8%) | 0.332 |