Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website https://www.jocmr.org

Review

Volume 13, Number 4, April 2021, pages 204-213


Review of COVID-19 Vaccines Approved in the United States of America for Emergency Use

Figures

Figure 1.
Figure 1. COVID-19 viral structure. COVID-19: coronavirus disease 2019.
Figure 2.
Figure 2. COVID-19 vaccines in clinical development phase. COVID-19: coronavirus disease 2019. Reference: Draft landscape of COVID-19 candidate vaccines. World Health Organization. http://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines. Accessed January 17, 2021.
Figure 3.
Figure 3. Route of administration of vaccines in clinical development phase. COVID-19: coronavirus disease 2019. Reference: Draft landscape of COVID-19 candidate vaccines. World Health Organization. http://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines. Accessed January 17, 2021.
Figure 4.
Figure 4. Injectable vaccines in clinical development phase. COVID-19: coronavirus disease 2019. Reference: Draft landscape of COVID-19 candidate vaccines. World Health Organization. http://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines. Accessed January 17, 2021.

Tables

Table 1. Vaccines Approved in USA and Other Countries for Emergency Use
 
Country of developmentDeveloperType of vaccineUsage
USA: United States of America; UK: United Kingdom; EU: European Union; UAE: United Arab Emirates.
USA/GermanyPfizer-BioNTechmRNAApproved in several countries. Emergency use in USA, EU, UK, Bahrain, Canada, Saudi Arabia, Mexico, etc.
USAModernamRNAApproved in Switzerland. Emergency use in USA, UK and EU
RussiaGamaleyaViral vectorEarly use in Russia
UK/SwedenOxford-AstraZenecaViral vectorEmergency use in UK and EU
ChinaCanSinoViral vectorApproved in China
USA/BelgiumJohnson and JohnsonViral vectorEmergency use in USA and Bahrain
RussiaVector InstituteProtein subunitEarly use in Russia
ChinaSinopharmInactivated virusApproved in China, UAE and Bahrain. Emergency use in Egypt
ChinaSinovacInactivated virusApproved in China. Emergency use in Brazil
ChinaSinopharm-WuhanInactivated virusLimited use in China and UAE
IndiaBharat biotechInactivated virusEmergency use in India

 

Table 2. Side Effects From Pfizer-BioNTech, Moderna and Janssen COVID-19 Vaccines
 
COVID-19 vaccineCommon side effectsOther adverse effects
COVID-19: coronavirus disease 2019.
Pfizer-BioNTechFever, cough, fatigue, headache, shortness of breath, chills, muscle pain, sore throat, diarrhea, or vomiting, local injection site redness or swelling.Lymphadenopathy, Bell’s palsy, paroxysmal ventricular arrhythmia, right leg paresthesia and shoulder injury.
ModernaFever, local pain, swelling, tenderness and erythema at the injection site. Axillary lymphadenopathy, fatigue, headache, myalgia, arthralgia, chills and nausea/vomiting.Hypersensitivity reactions, Bell’s palsy and some other lymphadenopathy.
JanssenMild to moderate febrile episode, injection site pain, fatigue, headache and myalgia.