| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Review
Volume 11, Number 7, July 2019, pages 465-471
Updates in Treatment of Recurrent Clostridium difficile Infection
Table
| Author | Sample (n) | Intervention | Comparison | Outcome in the FMT group | Follow-up period |
|---|---|---|---|---|---|
| RCT: randomized controlled trial; FMT: fecal microbiota transplantation; V: vancomycin; F: fidaxomicin; C: colonoscopy; E: enema; NJ: nasojejunal; ND: nasoduodenal. | |||||
| Van Nood et al 2013 [38] | 42 | FMT via ND tube preceded by V for 4 days and bowel lavage | V for 14 days and V for 14 days followed by bowel lavage | Resolution of symptoms in 15/16 (94%) patients | 5 weeks |
| G Cammarota et al 2015 [12] | 39 | V for 3 days followed by FMT via C | V for 10 days followed by every 2-3 days for 3 weeks | Resolution of symptoms in 18/20 (90%) patients | 10 weeks |
| Susy S. Hota et al 2017 [13] | 30 | V for 14 days followed by FMT via E | 6-week taper of V | Resolution of symptoms in 7/16 (43.8%) patients | 120 days |
| Hvas et al 2019 [39] | 64 | V for 4 - 10 days followed by FMT via C or NJ tube | V for 10 days, F for 10 days | Clinical resolution and negative CD test in 17/24 (71%) | 8 weeks |