Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
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Original Article

Volume 11, Number 6, June 2019, pages 435-446


Relationship of Anthropometric Indices to Abdominal Body Composition: A Multi-Ethnic New Zealand Magnetic Resonance Imaging Study

Figures

Figure 1.
Figure 1. Quantification of visceral adipose tissue volume (a), subcutaneous adipose tissue volume (b) and total abdominal volume (c).
Figure 2.
Figure 2. Comparison of VAT volume (a), SAT volume (b), and TAb volume (c) measurements between the independent raters. VAT: visceral adipose tissue; SAT: subcutaneous adipose tissue; TAb: total abdominal.

Tables

Table 1. Baseline Characteristics of the Study Participants
 
CharacteristicsTotalCaucasianMaori/PIOtherP
Data are presented as mean ± standard deviation or count values. aSignificant differences (P < 0.05). DM: diabetes mellitus; PI: Pacific Islanders.
No. of participants87372426
Age, years54.3 ± 1.658.6 ± 2.555.9 ± 2.246.6 ± 2.70.004a
Sex0.092
  Men56191819
  Women311867
Height, cm171.9 ± 1.1171.4 ± 1.4174.8 ± 2.3170.1 ± 2.00.221
Weight, kg85.8 ± 2.182.3 ± 2.297.3 ± 3.880.1 ± 4.00.002a
Body mass index, kg/m228.9 ± 0.728.0 ± 0.832.2 ± 1.527.4 ± 1.00.012a
Waist circumference, cm98.9 ± 1.696.8 ± 2.2106.3 ± 3.195.2 ± 2.70.019a
Prediabetes/DM0.715
  Yes59261716
  No2811710
Etiology of pancreatitis0.577
  Biliary3917814
  Alcohol-related15564
  Other3315108
Recurrence of pancreatitis0.972
  Yes22967
  No65281819
Time since pancreatitis, months28.0 ± 2.228.4 ± 3.231.7 ± 4.624.2 ± 4.10.445

 

Table 2. Ethnic Variations in MRI-Derived Abdominal Volumes
 
VAT volume (L)SAT volume (L)TAb volume (L)
β coefficient (95% CI)Odds ratio (95% CI)Pβ coefficient (95% CI)Odds ratio (95% CI)Pβ coefficient (95% CI)Odds ratio (95% CI)P
Model 1 was adjusted for age and sex. Model 2 was adjusted for age, sex and prediabetes/diabetes mellitus status. Model 3 was adjusted for age, sex, prediabetes/diabetes mellitus status, etiology, recurrence and time since acute pancreatitis. aSignificant associations (P < 0.05). PI: Pacific Islanders; SAT: subcutaneous adipose tissue; TAb: total abdominal; VAT: visceral adipose tissue; MRI: magnetic resonance imaging; CI: confidence interval.
Unadjusted
  CaucasianReferenceReferenceReference
  Maori/PI0.7292.073 (1.219 - 3.525)0.007a0.1851.203 (0.859 - 1.684)0.2830.2101.233 (1.012 - 1.503)0.038a
  Other0.0861.090 (0.639 - 1.859)0.751-0.0960.909 (0.635 - 1.301)0.602-0.0960.909 (0.747 - 1.105)0.338
Model 1
  CaucasianReferenceReferenceReference
  Maori/PI0.7532.124 (1.146 - 3.937)0.017a0.3581.431 (0.968 - 2.113)0.0720.1981.208 (0.985 - 1.480)0.069
  Other0.1651.179 (0.602 - 2.310 )0.631-0.0380.963 (0.950 - 1.443)0.854-0.1230.884 (0.708 - 1.105)0.279
Model 2
  CaucasianReferenceReferenceReference
  Maori/PI0.7552.128 (1.143 - 3.961)0.017a0.3741.433 (0.969 - 2.119)0.0720.1891.208 (0.985 - 1.481)0.069
  Other0.1771.193 (0.605 - 2.355)0.610-0.0440.957 (0.638 - 1.437)0.957-0.1280.880 (0.702 - 1.103)0.267
Model 3
  CaucasianReferenceReferenceReference
  Maori/PI0.7642.146 (1.095 - 4.209)0.026a0.3631.438 (0.940 - 2.200)0.0940.1801.197 (0.958 - 1.495)0.114
  Other0.2501.284 (0.609 - 2.710)0.511-0.1650.848 (0.544 - 1.323)0.848-0.1680.846 (0.662 - 1.080)0.179

 

Table 3. Ethnicity-Specific Associations Between Waist Circumference and Abdominal Volumes
 
VAT volume (L)aSAT volume (L)TAb volume (L)
R2β coefficient (95% CI)PR2β coefficient (95% CI)PR2β coefficient (95% CI)P
Model 1 was adjusted for age and sex. Model 2 was adjusted for age, sex and prediabetes/diabetes mellitus status. Model 3 was adjusted for age, sex, prediabetes/diabetes mellitus status, etiology, recurrence and time since acute pancreatitis. aData were log10 transformed. PI: Pacific Islanders; SAT: subcutaneous adipose tissue; TAb: total abdominal; VAT: visceral adipose tissue; CI: confidence interval.
Unadjusted
  Total0.37333.927 (24.383 - 43.470)< 0.0010.5397.194 (5.759 - 8.629)< 0.0010.6444.225 (3.548 - 4.902)< 0.001
  Caucasian0.36327.815 (14.973 - 40.658)< 0.0010.4216.590 (3.937 - 9.243)< 0.0010.5653.742 (2.615 - 4.869)< 0.001
  Maori/PI0.30742.250 (15.166 - 75.335)0.0050.5086.674 (3.769 - 6.580)< 0.0010.6875.183 (3.634 - 6.731)< 0.001
  Other0.32432.223 (12.603 - 51.844)0.0020.7157.376 (5.414 - 9.338)< 0.0010.6403.871 (2.647 - 5.095)< 0.001
Model 1
  Total0.46444.231 (33.662 - 54.801)< 0.0010.6488.228 (6.891 - 9.566)< 0.0010.6654.391 (3.703 - 5.078)< 0.001
  Caucasian0.40334.452 (18.137 - 50.767)< 0.0010.5567.291 (4.742 - 9.839)< 0.0010.5813.992 (2.670 - 5.314)< 0.001
  Maori/PI0.56951.165 (26.159 - 76.172)< 0.0010.6129.756 (5.176 - 14.336)< 0.0010.7464.779 (3.216 - 6.341)< 0.001
  Other0.35638.403 (13.714 - 63.091)0.0040.8247.653 (5.836 - 9.470)< 0.0010.6283.994 (2.397 - 5.591)< 0.001
Model 2
  Total0.46444.286 (33.646 - 54.926)< 0.0010.6518.254 (6.911 - 9.597)< 0.0010.6654.392 (3.700 - 5.083)< 0.001
  Caucasian0.41437.053 (19.208 - 54.898)< 0.0010.5567.299 (4.687 - 9.911)< 0.0010.5874.099 (2.730 - 5.468)< 0.001
  Maori/PI0.60749.434 (23.537 - 75.331)0.0010.6419.542 (4.994 - 14.090)< 0.0010.7504.686 (3.049 - 6.323)< 0.001
  Other0.36135.208 (5.759 - 64.656)0.0210.8247.708 (5.671 - 10.471)<0.0010.6294.078 (2.213 - 5.944)< 0.001
Model 3
  Total0.49446.450 (35.486 - 57.414)< 0.0010.6768.655 (7.272 - 10.038)< 0.0010.6924.540 (3.840 - 5.239)< 0.001
  Caucasians0.50738.766 (19.700 - 57.832)< 0.0010.6687.980 (5.216 - 10.743)< 0.0010.6434.051 (2.556 - 5.546)< 0.001
  Maori/PI0.72964.270 (35.571 - 92.969)< 0.0010.67811.404 (5.486 - 17.321)0.0010.8145.439 (3.609 - 7.269)< 0.001
  Other0.41739.052 (6.548 - 71.556)0.0210.9058.919 (6.915 - 10.924)< 0.0010.7594.928 (2.946 - 6.911)< 0.001

 

Table 4. Ethnicity-Specific Associations Between Body Mass Index and Abdominal Volumes
 
Ethnicity/modelVAT volume (L)aSAT volume (L)TAb volume (L)
R2β coefficient (95% CI)PR2β coefficient (95% CI)PR2β coefficient (95% CI)P
Model 1 was adjusted for age and sex. Model 2 was adjusted for age, sex and prediabetes/diabetes mellitus status. Model 3 was adjusted for age, sex, prediabetes/diabetes mellitus status, etiology, recurrence and time since acute pancreatitis. PI: Pacific Islanders; SAT: subcutaneous adipose tissue; Tab: total abdominal volume; VAT: visceral adipose tissue; CI: confidence interval. aData were log10 transformed.
Unadjusted
  Total0.33713.376 (9.301 - 17.451)< 0.0010.6883.354 (2.867 - 3.842)< 0.0010.7131.835 (1.584 - 2.086)< 0.001
  Caucasian0.41911.231 (6.621 - 15.841)< 0.0010.5922.885 (2.063 - 3.706)< 0.0010.7271.566 (1.237 - 1.895)< 0.001
  Maori/PI0.14215.029 (-0.900 - 30.959)0.0600.8154.039 (3.187 - 4.890)< 0.0010.7732.627 (1.998 - 3.256)< 0.001
  Other0.35712.843 (5.574 - 20.111)0.0010.7042.780 (2.021 - 3.539)< 0.0010.6721.507 (1.063 - 1.950)< 0.001
Model 1
  Total0.47019.295 (14.633 - 23.956)< 0.0010.7523.697 (3.218 - 4.176)< 0.0010.7692.014 (1.765 - 2.262)< 0.001
  Caucasian0.49515.300 (9.338 - 21.261)< 0.0010.7283.255 (2.509 - 4.000)< 0.0010.7831.807 (1.451 - 2.162)<0.001
  Maori/PI0.57918.979 (6.803 - 31.155)0.0040.8695.389 (4.115 - 6.657)< 0.0010.8752.285 (1.762 - 2.808)< 0.001
  Other0.37615.780 (4.688 - 26.873)0.0080.8142.869 (2.160 - 3.578)< 0.0010.6671.556 (0.982 - 2.129)< 0.001
Model 2
  Total0.47019.327 (14.628 - 24.025)< 0.0010.7583.715 (3.238 - 4.193)< 0.0010.7702.014 (1.764 - 2.264)< 0.001
  Caucasian0.49615.592 (9.125 - 22.058)< 0.0010.7383.205 (2.456 - 3.955)< 0.0010.7831.802 (1.431 - 2.173)< 0.001
  Maori/PI0.58818.324 (5.720 - 30.929)0.0070.8835.317 (4.074 - 6.560)< 0.0010.8752.275 (1.724 - 2.827)< 0.001
  Other0.39113.975 (1.093 - 26.856)0.0350.8152.821 (2.028 - 3.614)< 0.0010.6671.550 (0.879 - 2.220)< 0.001
Model 3
  Total0.49919.941 (15.057 - 24.825)< 0.0010.7693.846 (3.342 - 4.350)< 0.0010.7862.059 (1.802 - 2.316)< 0.001
  Caucasian0.52114.857 (7.817 - 21.898)< 0.0010.7453.149 (2.312 - 3.985)< 0.0010.8081.763 (1.378 - 2.148)< 0.001
  Maori/PI0.67621.205 (6.288 - 36.122)0.0080.8985.868 (4.273 - 7.463)< 0.0010.9152.436 (1.846 - 3.027)< 0.001
  Other0.44114.749 (0.047 - 29.4503)0.0490.8833.296 (2.454 - 4.138)< 0.0010.7401.813 (1.031 - 2.594)< 0.001

 

Table 5. Ethnicity-Specific Equations to Estimate VAT Volume
 
CaucasianMaori/PIOther
PVIFEquationPVIFEquationPVIFEquation
aP < 0.05 (statistical significance). In the equations, sex- men = 0, women = 1. BMI: body mass index; PI: Pacific Islanders; VAT: visceral adipose tissue; VIF: variance inflation factor; WC: waist circumference.
Age, years0.012a1.056Log10(VAT) = 11.99 (Age) - 1,216.08 (Sex) + 132.09 (BMI)0.2531.215Log10(VAT) = 54.00 (WC) - 1,134.07 (Sex)0.2461.011Log10(VAT) = 53.53 (WC) + 24.55 (Height)
Sex0.009a2.0900.022a2.7030.3741.806
BMI, kg/m20.003a2.001-127.740-14.646
WC, cm0.2212.1110.001a4.1200.010a1.930
Height, cm0.9332.1310.7532.6280.024a1.124
Weight, kg-172.1660.1783.971-27.468
Etiology0.9591.5770.3721.2940.3511.053
Recurrence0.9591.1740.1381.0920.4931.503
Time since pancreatitis, months0.4501.2080.0701.2190.1171.702