J Clin Med Res

Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc

Journal website http://www.jocmr.org

Original Article

Volume 11, Number 5, May 2019, pages 326-331

Prevalence of Documented Excessive Weight Gain Among Adolescent Girls and Young Women Using Depot Medroxyprogesterone Acetate

Figures

Figure 1. Flow of the study. DMPA: depot medroxyprogesterone acetate.

Figure 2. Body weight at baseline, 6 months after DMPA initiation and 12 months after DMPA initiation. DMPA: depot medroxyprogesterone acetate.

Figure 3. The trend of weight changes of each individual woman who has an excessive weight gain at 12 months after DMPA initiation. DMPA: depot medroxyprogesterone acetate.

Tables

**Table 1.** Baseline Characteristics of 231 DMPA Users
Characteristics	Total (n = 231), mean ± SD or n (%)	Early weight gainer (n = 28), mean ± SD or n (%)	Non-early weight gainer (n = 203), mean ± SD or n (%)	P
Adolescent: person aged 10 - 19 years; BMI: body mass index; DMPA: depot medroxyprogesterone acetate; COC: combined oral contraception. P value < 0.05 indicates statistical significance.
Age (years)	20.17 ± 2.64	19.67 ± 2.60	20.24 ± 2.60	0.291
Adolescent	92 (39.83)	13 (46.43)	79 (38.92)	0.538
Race				1.000
Thai	219 (94.81)	28 (100)	191 (94.09)
Burmese	5 (2.16)	0 (0)	5 (2.46)
Laos	6 (2.60)	0 (0)	6 (2.96)
Cambodian	1 (0.43)	0 (0)	1 (0.49)
Married or in-union status	220 (95.24)	24 (85.71)	196 (96.55)	0.032
BMI (kg/m²)	21.00 ± 3.49	21.21 ± 3.41	20.98 ± 3.51	0.746
Baseline weight (kg)	52.19 ± 9.46	52.86 ± 9.48	52.10 ± 9.47	0.691
Height (cm)	157.56 ± 6.30	157.67 ± 5.71	157.54 ± 6.39	0.917
Ever-use DMPA	33 (14.29)	9 (32.14)	24 (11.82)	0.008
Ever-use COC	118 (51.08)	14 (50.00)	104 (51.23)	1.000
Nulliparous	19 (8.23)	7 (25.00)	12 (5.91)	0.003
Parity (n = 212)				1.000
One	179 (84.43)	18 (85.71)	161 (84.29)
Two	30 (14.29)	3 (14.29)	27 (14.14)
Three or more	0 (0)	0 (0)	3 (1.57)

**Table 2.** Estimated Risk of Having Early Excessive Weight Gain in 231 DMPA Users
Factors	Relative risk	95% CI	P value
DMPA: depot medroxyprogesterone acetate. P value < 0.05 indicates statistical significance.
Unmarried or non-in union status	3.33	1.39 - 7.94	0.031
Ever-use DMPA	2.84	1.40 - 5.73	0.008
Nulliparous	3.71	1.81 - 7.60	0.003