Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 10, Number 7, July 2018, pages 588-592

The Impact of Nutritional Status and Complete Blood Count Parameters on Clinical Outcome in Geriatric Critically Ill Patients

Figures

Figure 1.
Figure 1. The relationship of platelet count and albumin level at the time of admission with motality.
Figure 2.
Figure 2. The relationship of platelet count and albumin level at the time of admission with microbiologically documented infection. MDI: microbiologically documented infection.

Tables

Table 1. Baseline Characteristics of Patients
 
All (n = 243), n (%)
APACHE II: acute physiology and chronic health evaluation score II.
Age (year) (± SD)78.96 ± 6.62
Gender
  Male104 (42.8%)
  Female139 (57.2%)
Number of comorbidities (median)3.0 (1.0 - 8.0)
APACHE II (median)26.0 (9.0 - 47.0]
Length of stay (mean ± SD)10.23 ± 8.68
Microbiologically documented infection
  Yes59 (24.2%)
  No184 (75.8%)
Final status
  Survivor144 (59.3%)
  Nonsurvivor99 (40.7%)

 

Table 2. Parameters and Their Relationship With Mortality
 
All Patients (n = 243)Survivors(n = 144)Non-survivors (n = 99)P
Median (range)Median (range)Median (range)
APACHE II: acute physiology and chronic health evaluation score II.
APACHE II26.0 (9.0 - 47.0)21.0 (9.0 - 40.0)31.0 (13.0 - 47.0)0
Albumin (g/dL)3.1 (1.1 - 4.9)3.2 (1.7 - 4.9)2.9 (1.1 - 4.7)0.001
Hemoglobin (g/dL)11.1 (5.0 - 17.6)11.3 (5.0 - 17.0)10.8 (6.4 - 17.6)0.454
Platelet (/mm3)197000.0 (15060.0 - 835300.0)199850.0 (15060.0 - 835300.0)178000.0 (25350.0 - 737000.0)0.095
Leukocyte (/mm3)12560.0 (1660.0 - 44160.07)11765.0 (1660.0 - 44160.0)12950.0 (3885.0 - 34610.0)0.19
Lymphocyte (/mm3)876.0 (79.0 - 9410.0)895.5 (172.0 - 9410.0)840.0 (79.0 - 3461.0)0.109
Mean platelet volume7.7 (4.3 - 16.2)7.6 (4.3 - 15.3)8.0 (4.4 - 16.2)0.26
Platelet/lymphocyte ratio205.3 (12.8 - 1675.0)201.8 (12.8 - 1236.6)205.3 (27.1 - 1675.0)0.838

 

Table 3. Pathogens of Microbiologically Documented Infection Episodes
 
All (n = 89) (%)
MRCoNS: methicillin-resistant coagulase-negative staphylococci.
Gram positive bacteria43 (48.3%)
  MRCoNS14
  Corynebacterium striatum11
  Enterococcus faecium6
  Others12
Gram negative bacteria31 (34.8%)
  Escherichia coli8
  Pseudomonas aeruginosa6
  Klebsiella Pneumoniae5
  Acinetobacter baumannii5
  Others7
Fungal agents15 (16.9%)
  Candida albicans10
  Candida tropicalis4
  Candida parapsilosis1

 

Table 4. Parameters and Their Relationship With Microbiologically Documented ınfection
 
All Patients (n = 243)Patients without MDI (n = 184)Patients with MDI (n = 59)P
Median (range)Median (range)Median (range)
APACHE II: acute physiology and chronic health evaluation score II; MDI: microbiologically documented infection.
APACHE II26.0 (9.0 - 47.0)23.0 (9.0 - 44.0)31.0 (16.0 - 47.0)0
Albumin (g/dL)3.1 (1.1 - 4.9)3.2 (1.1 - 4.9)2.9 (1.6 - 4.0)0.004
Hemoglobin (g/dL)11.1 (5.0 - 17.6)11.3 (5.0 - 17.2)10.8 (6.4 - 17.6)0.573
Leukocyte (/mm3)12560.0 (1660.0 - 44160.0)12280.0 (1660.0 - 44160.0)12950.0 (5420.0 - 3743.0)0.487
Platelet (/mm3)197000.0 (15060.0 - 835300.0)192050.0 (15060.0 - 831200.0)215000.0 (50760.0 - 835300.0)0.097
Lymphocyte (/mm3)876.0 (79.0 - 9410.0)865.0 (79.0 - 9141.0)962.0 (221.0 - 9410.0)0.636
Mean platelet volume7.7 (4.3 - 16.2)7.6 (4.3 - 16.2)7.9 (4.4 - 13.3)0.538
Platelet/lymphocyte ratio205.3 (12.8 - 1675.0)195.8 (12.8 - 1675.0)219.8 (27.1 - 1102.7)0.398