Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 10, Number 5, May 2018, pages 391-395

Sidestream Dark Field Imaging of the Microcirculation to Assess Preeclampsia Microvascular Dysfunction

Figures

Figure 1.
Figure 1. Flow diagram of patient screening, recruitment and analysis from September 2014 to July 2016.
Figure 2.
Figure 2. MFI (a), TVD (b), PVD (c), and PPV (d) in participants who did not develop preeclampsia (n = 54) and those who developed preeclampsia (n = 12). The participants who developed severe preeclampsia are included in the preeclampsia group.

Tables

Table 1. Participant Characteristics at the Time of Sidestream Dark Field Imaging
 
CharacteristicNo preeclampsia (n = 54)Preeclampsia (n = 10)Severe preeclampsia (n = 2)
*Several patients were enrolled who met more than one inclusion criterion. Data are presented as n (%) or mean ± standard deviation (SD).
Age (years)31.7 ± 3.931.0 ± 4.132.5 ± 5.0
BMI (kg/m2)31.4 ± 9.832.4 ± 8.235.1 ± 1.0
Gestational age (weeks)19.2 ± 1.719.8 ± 1.719.3 ± 0.6
Inclusion criteria (n (%))*
  Previous preeclampsia11 (20.4)4 (40)0
  Pre-existing renal disease2 (3.7)1 (10)0
  Pre-existing diabetes mellitus18 (33.3)1 (10)1 (50)
  Antiphospholipid syndrome1 (1.9)1 (10)0
  BMI ≥ 3529 (53.7)3 (30)1 (50)
  Pre-existing hypertension5 (9.3)2 (20)0
  Multiple pregnancy4 (7.4)4 (40)1 (50)
  Age > 40 years3 (5.6)00
  Family history of preeclampsia1 (1.9)00

 

Table 2. : Microcirculation Indices in Participants With no Preeclampsia, Preeclampsia, and Severe Preeclampsia
 
Microcirculatory ParameterNo preeclampsia (n = 54)Preeclampsia (n = 10)Severe preeclampsia (n = 2)
Data are presented as means ± SD.
MFI2.75 ± 0.382.79 ± 0.342.79 ± 0.34
TVD (n/mm)17.99 ± 4.6217.12 ± 4.1217.14 ± 3.62
PVD (n/mm)14.32 ± 5.4714.06 ± 4.8215.23 ± 4.43
PPV (%)79.38 ± 21.3882.86 ± 21.1087.76 ± 13.07