Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
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Case Report

Volume 9, Number 1, January 2017, pages 74-78

Magnetic Resonance Spectroscopy and Single-Photon Emission Computed Tomography in the Evaluation of Cerebral Tumors: A Case Report


Figure 1.
Figure 1. MRI images in coronal (a), sagittal (b) and axial plane (c) demonstrating the area of the tumor where the voxel of the performed MRS study (d) was obtained.
Figure 2.
Figure 2. 1H-MRS of the tumor area (left) showing the high Chol/NAA ratio in comparison to the normal MRS findings of the opposed normal brain tissue (right).
Figure 3.
Figure 3. Axial images of the performed brain SPECT with technetium-99m (Tc99m) demonstrating high standardized uptake value (SUV).
Figure 4.
Figure 4. The tumor cells form lobules some partly demarcated by thin collagenous septae (hematoxylin and eosin stain, original magnification × 10).
Figure 5.
Figure 5. The tumor cells are uniform with oval nuclei with delicate chromatin that on occasion show central clearing or the formation of nuclear inclusions. Psammoma bodies are present (hematoxylin and eosin stain, original magnification × 40).


Table 1. The Ratios of NAA/Cr, Chol/Cr, and Chol/NAA According to the Performed 1H-MRS Study
Lesion site (right hemisphere)Normal brain tissue (left hemisphere)Deviation
Chol: choline; Cr: creatinine; NAA: N-acetylaspartate.
NAA/Cr1.561.63(-) 4
Chol/Cr4.051.15(+) 252
Chol/NAA2.030.709(+) 186