Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 8, Number 12, December 2016, pages 859-862

Clinical Impact of Blood Culture Results in Acutely Ill Hospitalized Adult Patients With Cystic Fibrosis

Tables

Table 1. Frequency of Bacterial and Fungal Related Venous Access Device Infections and Associated Bacteremia and Fungemia in Adult Patients (n = 31) With Cystic Fibrosis (2001 - 2015)
 
PatientsEventsPositive blood cultures
TIVAP: totally implantable venous access ports. Event: single temporal identified infectious complication-noting multiple patients had more than one event. Three positive (+) blood cultures were polymicrobial.
Bacterial: catheter infections4614
Fungal: catheter infections112
Bacterial: TIVAP infections132348
Fungal: TIVAP infections131742
Total3147106

 

Table 2. Venous Access Device Related Blood Stream Infections in Adult Patients (n = 31) With Cystic Fibrosis (2001 - 2015): Frequency (numerical value relates to total number of positive blood cultures) and Species of Pathogenic Infecting Microbial Agent
 
BacterialFungal
Catheter-related blood stream infections
Enterococcus faecalis (not VRE): 6Candida glabrata: 2
Coagulase-negative Staphylococcus: 4
Methicillin-resistant Staphylococcus aureus: 1
Vancomycin-resistant Enterococcus faecalis (VRE): 3
Totally implantable venous access port (TIVAP) blood stream infections
Methicillin-resistant Staphylococcus aureus: 18Candida albicans: 22
Coagulase-negative Staphylococcus: 10Candida glabrata: 12
Vancomycin-resistant Enterococcus faecalis (VRE): 1Candida tropicalis: 6
Enterococcus faecalis (not VRE): 4Candida parapsilosis: 2
Methicillin-sensitive Staphylococcus aureus: 4
Serratia marcescens: 3
Enterobacter aerogenes: 3
Pseudomonas aeruginosa: 2
Enterobacter cloacae: 1
Flavobacterium species: 1
Klebsiella oxytoca: 1

 

Table 3. Lung-Specific Related Blood Stream Infections in Adult Patients With Cystic Fibrosis (n = 10) (2001 - 2015): Frequency (Numerical Value Relates to Total Number Positive Blood Cultures) and Species of Pathogenic Infecting Microbial Agent
 
*Cause of death.
Methicillin-resistant Staphylococcus aureus6
Methicillin-resistant Staphylococcus aureus1
Methicillin-resistant Staphylococcus aureus + Pseudomonas aeruginosa1
Hemophilus influenza1
Stenotrophomonas maltophilia1
Burkholderia cepacia complex4*
Burkholderia cepacia complex1*
Burkholderia cepacia complex (+ cavitary lung disease)2
Burkholderia cepacia complex (+ cavitary lung disease)1*
Burkholderia cepacia complex (+ cavitary lung disease)1

 

Table 4. Non-Lung Organ-Specific Related Blood Stream Infections in Adult Patients With Cystic Fibrosis (n = 9) (2001 - 2015): Frequency (Numerical Value Relates to Total Number Positive Blood Cultures) and Species of Pathogenic Infecting Microbial Agent
 
*Cause of death. PEG: percutaneous endoscopic gastrostomy.
Endocarditis (tricuspid valve)Methicillin-resistant Staphylococcus aureus3
Pyelonephritis/kidney abscessCandida glabrata4*
PyelonephritisAlcaligenes xylosoxidans3
Urinary tract infection with sepsisEnterococcus faecalis (not VRE) and methicillin-resistant Staphylococcus aureus2, 2
PEG tube/abdominal wall cellulitisMethicillin-resistant Staphylococcus aureus3
PEG tube/abdominal wall cellulitisMethicillin-resistant Staphylococcus aureus1
Wound dehiscence/bowel evisceration/peritonitisCandida glabrata and Candida parapsilosis3*, 2*
Spontaneous bacterial peritonitis/cirrhosisKlebsiella pneumoniae and methicillin-resistant Staphylococcus aureus1, 1
Presumed intestinalSalmonella species: S. muenster serogroup 1 + S. alachla serogroup 01