J Clin Med Res

Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc

Journal website http://www.jocmr.org

Original Article

Volume 8, Number 9, September 2016, pages 667-673

Prevalence of Metabolic Syndrome and Its Clinical and Angiographic Profile in Patients With Naive Acute Coronary Syndrome in North Indian Population

**Table 1.** Baseline Characteristics of Patients (n = 648)
Characteristics	MetS (n = 244)	No MetS (n = 404)	P-value
Age (years)	60.3 ± 8.4	57.6 ± 7.9	0.07
Female	86 (35.24%)	98 (24.25%)	0.04
Diabetes mellitus	114 (46.72%)	88 (21.78%)	< 0.001
Hypertension	154 (63.11%)	134 (33.16%)	< 0.001
Family history of CAD	58 (23.77%)	92 (22.7%)	0.43
Abdominal obesity	116 (47.54%)	90 (22.27)	0.005
Tobacco abuse	74 (30.32%)	172 (42.57%)	< 0.001
BMI (kg/m²)	31.6 ± 3.4	25.2 ± 2.8	0.01
Serum HDL-C (mg/dL)	32.7 ± 5.9	41.6 ± 4.8	0.005
Serum TG (mg/dL)	228.6 ± 56.3	132.3 ± 38.5	0.006
STEMI	102 (41.80%)	258 (63.86%)	0.002
NSTEACS	142 (58.19%)	146 (36.14%)	0.003
Cardiogenic shock	66 (27.04%)	70 (17.32%)	0.02
Ejection fraction (%)	47.3 ± 8.2	50.35 ± 6.5	0.11
Recurrent ischemia	36 (14.75%)	30 (7.42%)	0.01
Mortality	8 (6.55%)	11 (5.44%)	0.23

Table 1. Baseline Characteristics of Patients (n = 648)

Characteristics

MetS (n = 244)

No MetS (n = 404)

P-value

Age (years)

60.3 ± 8.4

57.6 ± 7.9

0.07

Female

86 (35.24%)

98 (24.25%)

0.04

Diabetes mellitus

114 (46.72%)

88 (21.78%)

< 0.001

Hypertension

154 (63.11%)

134 (33.16%)

< 0.001

Family history of CAD

58 (23.77%)

92 (22.7%)

0.43

Abdominal obesity

116 (47.54%)

90 (22.27)

0.005

Tobacco abuse

74 (30.32%)

172 (42.57%)

< 0.001

BMI (kg/m²)

31.6 ± 3.4

25.2 ± 2.8

0.01

Serum HDL-C (mg/dL)

32.7 ± 5.9

41.6 ± 4.8

0.005

Serum TG (mg/dL)

228.6 ± 56.3

132.3 ± 38.5

0.006

STEMI

102 (41.80%)

258 (63.86%)

0.002

NSTEACS

142 (58.19%)

146 (36.14%)

0.003

Cardiogenic shock

66 (27.04%)

70 (17.32%)

0.02

Ejection fraction (%)

47.3 ± 8.2

50.35 ± 6.5

0.11

Recurrent ischemia

36 (14.75%)

30 (7.42%)

0.01

Mortality

8 (6.55%)

11 (5.44%)

0.23

**Table 2.** Baseline Angiographic Characteristics of Patients (n = 648)
Characteristics	MetS (n = 244)	No MetS (n = 404)	P-value
SVD: single vessel disease; DVD: double vessel disease; TVD: triple vessel disease; LMCA: left main coronary artery. *Lesion characteristics based on ACC/AHA Subcommittee for Percutaneous Transluminal Coronary Angioplasty.
Angiographic profile of CAD
Recanalized	14 (5.73%)	28 (6.94%)	0.001
SVD	54 (21.13%)	218 (53.96%)	0.001
DVD	96 (39.34%)	98 (24.26%)	0.001
TVD	48 (19.67%)	42 (10.39%)	0.001
LMCA	32 (13.11%)	18 (4.45%)	0.001
Lesion characteristics*
Type A	80 (32.78%)	202 (50%)	0.01
Type B	100 (40.98%)	128 (31.68%)	0.01
Type C	64 (26.23%)	74 (18.32%)	0.01

Table 2. Baseline Angiographic Characteristics of Patients (n = 648)

Characteristics

MetS (n = 244)

No MetS (n = 404)

P-value

SVD: single vessel disease; DVD: double vessel disease; TVD: triple vessel disease; LMCA: left main coronary artery. *Lesion characteristics based on ACC/AHA Subcommittee for Percutaneous Transluminal Coronary Angioplasty.

Angiographic profile of CAD

Recanalized

14 (5.73%)

28 (6.94%)

0.001

SVD

54 (21.13%)

218 (53.96%)

0.001

DVD

96 (39.34%)

98 (24.26%)

0.001

TVD

48 (19.67%)

42 (10.39%)

0.001

LMCA

32 (13.11%)

18 (4.45%)

0.001

Lesion characteristics*

Type A

80 (32.78%)

202 (50%)

0.01

Type B

100 (40.98%)

128 (31.68%)

0.01

Type C

64 (26.23%)

74 (18.32%)

0.01

**Table 3.** Various Criteria Proposed for Metabolic Syndrome
Criteria	Modified WHO	NCEP-ATP III (2001)	Modified NCEP-ATP III (2004)
BP: blood pressure; FPG: fasting plasma glucose; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol.
	DM, IGT, IFG or insulin resistance with ≥ 2 of the following	≥ 3 of the following	≥ 3 of the following
FPG (mg/dL)		> 110	> 110
Obesity	BMI > 30 kg/m² or WHR > 0.9 for men and > 0.85 for men	Waist circumference > 102 cm in men and > 88 cm in women	Waist circumference > 90 cm in men and > 80 cm in women
BP (mm Hg)	≥ 140/90 or on medication	SBP > 130 and/or DBP > 85 or medical treatment of previously diagnosed hypertension	SBP > 130 and/or DBP > 85 or medical treatment of previously diagnosed hypertension
TG (mg/dL)	> 150 (1.7 mmol/L)	> 150 (1.7 mmol/L)	> 150 (1.7 mmol/L)
HDL-C (mg/dL)	< 35 (0.9 mmol/L) for men and 39 (1.0 mmol/L) for women	< 40 (1.03 mmol/L) in men and < 50 in women (1.29 mmol/L)	< 40 in men and < 50 in women

Table 3. Various Criteria Proposed for Metabolic Syndrome

Criteria

Modified WHO

NCEP-ATP III (2001)

Modified NCEP-ATP III (2004)

BP: blood pressure; FPG: fasting plasma glucose; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol.

DM, IGT, IFG or insulin resistance with ≥ 2 of the following

≥ 3 of the following

FPG (mg/dL)

> 110

Obesity

BMI > 30 kg/m² or WHR > 0.9 for men and > 0.85 for men

Waist circumference > 102 cm in men and > 88 cm in women

Waist circumference > 90 cm in men and > 80 cm in women

BP (mm Hg)

≥ 140/90 or on medication

SBP > 130 and/or DBP > 85 or medical treatment of previously diagnosed hypertension

TG (mg/dL)

> 150 (1.7 mmol/L)

HDL-C (mg/dL)

< 35 (0.9 mmol/L) for men and 39 (1.0 mmol/L) for women

< 40 (1.03 mmol/L) in men and < 50 in women (1.29 mmol/L)

< 40 in men and < 50 in women