| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Review
Volume 2, Number 1, February 2010, pages 18-22
Recurrent Pregnancy Loss and Thrombophilia
Table
| Clinical Criteria (Vascular thrombosis of arterial and/or venous vessels in any tissue or organ) Pregnancy morbidity | Laboratory Criteria |
|---|---|
| For more details we suggest to consult Miyakis S, et al. J Thromb Haemost. 2006;4:295-306 [50]. | |
| One or more unexplained deaths of a morphologically normal fetus at or beyond the 10th week of gestation | Lupus anticoagulant present in plasma, on two or more occasions at least 12 weeks apart, detected according to the International Society of Thrombosis and Haemostasis (ISTH) |
| One or more unexplained deaths of a morphologically normal neonate before the 34th week of gestation because of eclampsia or severe eclampsia or placental insufficiency | Anticardiolipin antibody (aCL) of IgG and/or IgM isotype in serum or in plasma present in medium or high titer on two or more occasions at least 12 weeks apart |
| Three or more unexplained consecutive spontaneous abortions before the 10th week of gestation | Anti-β2 glycoprotein-I antibody of IgG and/or IgM isotype in serum or in plasma present on two or more occasion at least 12 weeks apart |