Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
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Case Report

Volume 7, Number 1, January 2015, pages 65-68

Immune Reconstitution Inflammatory Syndrome Mimicking Progressive Multifocal Leucoencephalopathy in a Multiple Sclerosis Patient Treated With Natalizumab: A Case Report and Review of the Literature


Figure 1.
Figure 1. MRI on initial relapse reveals a new lesion in the subcortical white matter of the right parietal lobe with high signal on the FLAIR sequence (arrows, a) and mild contrast enhancement (arrow, b).
Figure 2.
Figure 2. MRI 2 months after demonstrating a resolution of the lesion of the right parietal lobe (a) and absence of gadolinium enhancement (b).
Figure 3.
Figure 3. On month 4, MRI demonstrates a new 2-cm lesion in the left cerebellar hemisphere with high signal on FLAIR (arrow, a) and a speckled pattern of contrast enhancement on the post-gadolinium image (arrow, b).
Figure 4.
Figure 4. On a follow-up MRI scan 12 months after the initial relapse, FLAIR images reveal complete resolution of the signal abnormalities in the left cerebellar hemisphere (a) and in the right parietal lobe (b).