Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 5, Number 1, February 2013, pages 22-25


Histology of the Oral Mucosa in Patients With BRONJ at III Stage: A Microscopic Study Proves the Unsuitability of Local Mucosal Flaps

Figure

Figure 1.
Figure 1. An inflammation of the mucosa with massive presence of plasma cells and granulocytes in the connective tissue was found in the samples taken from above the necrotic bone (A). (B) A conservation of the connective tissue isto-architecture and of deeper epithelial layers was found on the samples of the mucosa surrounding the osteonecrosis. The inflammatory infiltrate is poorly represented and small areas of cellular plasma densification are rarely noticeable. Despite the mucosa deep layers keep their original architecture, the superficial ones are characterized by the presence of swollen and hypereosinophilic cells with a picnotic nucleus, which represents the signs of pathognomonic cell suffering.