| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Original Article
Volume 9, Number 10, October 2017, pages 860-863
Obstetric Outcomes of Twin Pregnancies in Japanese Women Aged 40 and Older
Tables
| Control | Advanced age | P-value | |||
|---|---|---|---|---|---|
| Number | % | Number | % | ||
| Data are presented as number with percentage or mean ± SD. | |||||
| Total | 536 | 117 | |||
| Maternal age at delivery | |||||
| Range | 25 - 29 | 40 - 45 | |||
| Average | 27.9 ± 0.8 | 41.9 ± 0.7 | |||
| Nulliparous | 358 | 67 | 53 | 45 | < 0.01 |
| Maternal height | 156 ± 6 | 157 ± 7 | 0.68 | ||
| Prepregnancy body mass index | 22.0 ± 3.5 | 22.3 ± 3.1 | 0.55 | ||
| Body mass index at delivery | 27.5 ± 3.7 | 27.3 ± 3.5 | 0.48 | ||
| In vitro fertilization | 0 | 0 | 38 | 32 | < 0.01 |
| Egg donor | 0 | 0 | 0 | 0 | 1 |
| Fetal reduction | 0 | 0 | 1 | 1 | 0.18 |
| Monochorionic twin pregnancy | 204 | 38 | 41 | 35 | 0.46 |
| Chronic hypertension | 0 | 0 | 1 | 1 | 0.18 |
| Pregestational diabetes | 0 | 0 | 0 | 0 | 1 |
| Low-dose aspirin in pregnancy | 0 | 0 | 0 | 0 | 1 |
| Uterine myoma with a diameter of 4 cm or more | 36 | 7 | 15 | 13 | 0.04 |
| Control | Advanced age | P-value | |||
|---|---|---|---|---|---|
| Number | % | Number | % | ||
| Data are presented as number with percentage. HELLP: hemolytic, elevated liver enzymes and low platelet. | |||||
| Total | 536 | 117 | |||
| Gestational age at delivery | |||||
| < 28 weeks | 12 | 2 | 0 | 0 | 0.14 |
| < 32 weeks | 40 | 7 | 1 | 1 | 0.01 |
| < 34 weeks | 72 | 13 | 16 | 14 | 0.95 |
| < 37 weeks | 303 | 57 | 75 | 64 | 0.15 |
| Cesarean delivery | |||||
| Elective | 351 | 65 | 80 | 68 | 0.59 |
| After labor | 42/185 | 23 | 11/37 | 30 | 0.40 |
| Hypertensive disorder | 48 | 9 | 17/116 | 15 | 0.09 |
| HELLP syndrome | 0 | 0 | 3 | 3 | < 0.01 |
| Gestational diabetes | 8 | 1 | 0 | 0 | 0.36 |
| Placental abruption | 6 | 1 | 1 | 1 | 1.00 |
| Placenta previa | 1 | 0 | 0 | 0 | 1.00 |
| Either twin fetal demise | 0 | 0 | 0 | 0 | 1.00 |
| At 12 - 21 weeks | 0 | 0 | 0 | 0 | 1.00 |
| At ≥ 22 weeks | 3 | 1 | 0 | 0 | 0.96 |
| Birth weight of smaller twin | |||||
| < 1,500 g | 33/533 | 6 | 15 | 13 | 0.02 |
| < 2,500 g | 476/533 | 88 | 112 | 96 | 0.04 |
| Birth weight of larger twin | |||||
| < 1,500 g | 70 | 13 | 4 | 3 | < 0.01 |
| < 2,500 g | 461 | 86 | 81 | 69 | < 0.01 |
| Birth weight discordance ≥ 20% | 33 | 6 | 9 | 8 | 0.53 |
| Neonatal outcomes of first twin | |||||
| Apgar score at 1 min < 7 | 18 | 3 | 0 | 0 | 0.06 |
| Apgar score at 5 min < 7 | 1 | 0 | 0 | 0 | 1.00 |
| Neonatal outcomes of first twin | |||||
| Apgar score at 1 min < 7 | 33/533 | 16 | 2 | 2 | 0.07 |
| Apgar score at 5 min < 7 | 1/533 | 0 | 0 | 0 | 1.00 |
| Postpartum hemorrhage requiring transfusion | 8 | 2 | 4 | 4 | 0.24 |