J Clin Med Res

Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc

Journal website http://www.jocmr.org

Original Article

Volume 7, Number 6, June 2015, pages 417-421

A Prospective Study on Red Blood Cell Transfusion Related Hyperkalemia in Critically Ill Patients

Figure

Figure 1. Linear correlation between number of days and serum potassium (K⁺) level.

Tables

**Table 1.** Patient Characteristics
Gender	N = 125	%
Female	71	56
Male	54	43.2
Age	63 (median)	22 - 92 years
Indication for PRBC transfusion
Acute blood loss	25	16.6
Coronary artery disease with NSTEMI	25	16.6
Septic shock	61	49
Invasive procedure	14	11.2
No. of PRBC transfusions
1 unit	104	83.2
2 units	11	8.8
3 units	9	7.2
7 units	1	0.8
Intravenous access
Central line	72	57.6
Peripheral line	53	42.4
Age of blood	15 days	2 - 36 days
Medications
ACE /ARB inhibitors	21	16.8
Spironolactone	8	6.4
Insulin	38	30.4
Diuretics	66	52.8
Morbidities
Acidosis (pH < 7.3)	63	50.4
Acute renal failure	75	60
End-stage renal disease	12	9.6

**Table 2.** Univariate and Multivariate Analysis of Factors Affecting K⁺ Value
Factors affecting K⁺ value	Univariate	95% confidence interval	Multivariate	95% confidence interval
Change in K⁺ value pre- and post-transfusion	0.2	0.58 - 1.93	0.3	0.31 - 2.88
Acidosis	0.1	0.22 - 1.67	0.2	0.62 - 3.02
Acute renal failure	0.64	0.28 - 3.33	0.55	0.47 - 2.17
End-stage renal disease	0.52	0.26 - 2.12	0.97	0.91 - 4.92
No. of transfusions	0.11	0.12 - 1.83	0.32	0.48 - 2.25
Age of RBC blood	0.02	0.32 - 0.91	0.04	0.14 - 0.91
K⁺ infusion via central access vs. peripheral access	0.43	0.75 - 4.17	0.82	0.76 - 3.93