Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Short Communication

Volume 7, Number 4, April 2015, pages 257-261


Inflammatory Bowel Disease as a Risk Factor for Premature Coronary Artery Disease

Table

Table 1. Correlation Between IBD and CAD
 
StudyPatient populationResult
Dagli et al [5]IBD: 40
Healthy patients: 40
IBD patients had a significant increase in carotid intimal media thickness (cIMT) compared to the control group (P = 0.01)
Dorn et al [6]CD: 4,532
UC: 9,533
SMR = 0.7 - 1.5 (NS)
SMR = 0.5 - 1.1 (NS)
Kristensen et al [7]CD: 4,732
UC: 13,622
Relative risk of myocardial infarction = 1.49 (CI: 1.16 - 1.93) in patients with an active flare and 2.05 (CI: 1.58 - 2.65) in chronic disease state
Yarur et al [8]CD: 173
UC: 183
Adjusted hazard ratio for developing CAD in IBD group = 4.08 (95% CI: 2.49 - 6.70)
Papa et al [9]IBD: 52
Healthy patients: 20
cIMT significantly higher in IBD patients (0.63 ± 0.15 mm) compared with controls (0.53 ± 0.08 mm) (P = 0.008)
Ruisi et al (current study)IBD: 300SMR = 0.0 (NS) 99.7% of the study patients did not have any reported CV events over the 2-year follow-up period