Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 1, Number 3, August 2009, pages 137-143

Tissue Factor Expression in the Symptomatic Carotid Plaque

Figures

Figure 1.
Figure 1. Diffuse TF immuno-reactivity in the core of a symptomatic patient.
Figure 2.
Figure 2. Diminished TF immuno-reactivity in the core of an asymptomatic patient.
Figure 3.
Figure 3. Scatter Plot of TF positive staining area in the Plaque Cores of Asymptomatic and Symptomatic Patients (units are expressed in μm2).
Figure 4.
Figure 4. Scatter Plot of TF positive staining area in the Plaque Caps of Asymptomatic and Symptomatic Patients (units are expressed in μm2).
Figure 5.
Figure 5. Box and Whisker plots, which show, increased TF Expression in the Plaque Cores of the most recently Symptomatic Patients.

Tables

Table 1. Clinical features of symptomatic and asymptomatic patients with high-grade ICA stenosis (≥70%)
 
Age (mean ± SD)Sex (Male)
All Patients (n=37)69 ± 727
Asymptomatic (n=4)72 ± 41
Symptomatic (n=33)69 ± 926
Time Since SymptomsNumberSex (Male)
  Asymptomatic41
  1-6 Months1716
  < 1 Month1610
Type of SymptomsNumberSex (Male)
  Asymptomatic41
  TIA/AF265
  Stroke721

 

Table 2. TF positive staining area in asymptomatic and symptomatic patients
 
AsymptomaticSymptomaticP Value
TF Cap379.1
[301.4-703.2]		37296.2
[32067.6-43648.7]		0.0010
TF Core399.8
[282.2-710.4]		52689.2
[39798.5-70827.0]		0.0010

 

Table 3. Increased TF positive staining area in the plaque cores of the most recently symptomatic patients
 
Asymptomatic< 1 Month1-6 MonthsP Value
TF Core399.8
[282.2-710.4]		64386.2
[38320.6-75970.5]		46286.7
[39698.5-63462.7]		0.0030